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35: Diarrhea


A 31-year old female presents with 5 days of abdominal pain and diarrhea, now with blood.  She states she has had a few similar episodes in the past, but this is worse.  She has never seen a doctor for it.  She is otherwise healthy.

On exam her vitals are normal.  She is tender in the right lower quadrant.  Rectal exam shows a small amount of stool with a little gross blood.

Her UA and pregnancy tests are negative.  Her CBC is normal except for a mild microcytic anemia with a hemoglobin of 10.1.  LFT’s and metabolic panel are normal.  A CT scan is ordered and one cut is shown below.  What does it show?  What is the significance.

sacroiliitis.JPG

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Answer: Sclerosis of the Sacro-Iliac joint

sacroiliitis2.JPG

This CT shows Sacro-iliitis which when it co-occurs with bloody diarrhea is highly suspicious for Inflammatory Bowel Disease.  The CT also showed a bladder stone and an appendicolith, but no evidence of acute appendicitis. The patient was diagnosed with Ulcerative Colitis.

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EXCERPT ON INFLAMMATORY BOWEL DISEASE

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Basics:       Idiopathic inflammatory.  Onset usually age 35-50.  Bloody diarrhea, pain.
Comps:      Anemia, obstruciton, cancer, arthritis, uveitis, kidney stones
Skin:          Erytema nodosum, Pyoderma gangrenosum
Rx:              Steroids, asacol, flagyl, remicade…
Surgery:     Refractory bleed, obstruction, perforation, abscess, megacolon
Dispo:         Admit: bad electrolytes, fever.

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