P5: Altered after OD

History of Present Illness:

A patient in their mid-20’s is brought to the hospital with ALOC following a Maxalt and Lamictal OD.

Vital Signs & Physical Exam:

Vital signs are notable for tachycardia and elevated BP.  She is altered but non-focal and a bit tremulous

 

Initial Diagnostic Testing:

  • CBC: normal except for WBC 12
  • Chem-7: normal except for Na 131
  • Other: Beta HCG normal, tox screen normal

What is the most likely diagnosis?

  • A) Stimulant OD
  • B) Serotonin syndrome
  • C) Alcohol withdrawal
  • D) Seizure

SCROLL DOWN FOR ANSWERS & 1-MINUTE CONSULT

 

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QUIZ ANSWER:

  • A) Stimulant OD – good thought but she is sleepy
  • B) Serotonin syndrome – CORRECT – can be caused by triptans
  • C) Alcohol withdrawal – good thought
  • D) Seizure – serotonin syndrome can mimic seizure

1-Minute Consult on this topic: Click HERE and scroll to page 316.

 

CASE CONCLUSION: treated with benzos and admitted to ICU on 5150 hold.  She did not require cyproheptadine.  She got worse for about 12 hours then gradually improved and was discharged to a psychiatric facility.