Triage: Decreased PO intake and vomiting for 4 days, feeling weak, states has lost 19lbs in 2 months
History of Present Illness: A man in his mid 50’s presents with 2 months of weight loss of 20 pounds due to anorexia and 2 days of generalized weakness and vomiting. He denies abdominal pain or diarrhea. He has a history of HTN and alcohol use disorder but says he has been sober for 3 weeks.
Vital Signs: 36.7, pulse of 122, RR of 16, BP of 139/66.
Physical Exam: Quite thin but not cachectic. Hard of hearing. Mild epigastric tenderness
An ECG is done

Computer Read: Sinus tach at 116, ST deviation and moderate T wave abnormality consider inferior ischemia
What is the most likely cause of ECG findings in this patient?
- A) None of the below
- B) Blood clot (PE)
- C) ACS
- D) Drug toxicity
- E) Electrolyte issue
ANSWERS & 1-MINUTE CONSULT
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My ECG interpretation: There is sinus tachycardia at 116, as well as ST deviation and moderate T wave abnormality but there are other causes than ischemia, such as an electrolyte abnormality, which fits much better with the clinical picture. Here it is most suggestive of hypokalemia

ANSWER:
- A) None of the below
- B) Blood clot (PE)
- C) ACS
- D) Drug toxicity
- E) Electrolyte issue- CORRECT – K was 2.5
1-Minute Consult on this topic: Click HERE and scroll to hypokalemia
CASE CONCLUSION: Admitted for oral and IV potassium repletion. His blood pressure medications were also switched to get him off a thiazide diuretic. His magnesium was also low and was repleted. With there measures his potassium normalized and he was discharge home the next afternoon
CASE LESSONS:
- Electrolyte abnormalities often cause ECG abnormalities that can mimic ischemia
- Common causes of hypokalemia include diarrhea, medications like HCTZ or PPIs as well as low magnesium and alcohol abuse
