Triage: Sent from PCP for room air sats 89%. Pt reports SOB and chest pain over past 4 days. Slight dry cough but no fevers, taking Prednisone x 4 months for arthritis
History of Present Illness: A woman in their mid-70’s here for shortness of breath and cough and chills for the last 4 days with some mild chest discomfort that is not exertional. Triage note is not accurate. On prednisone 20mg for RA v. temporal arteritis
Vital Signs: T: 36.9 °C (Oral) HR: 76 (Monitored) RR: 18 BP: 166/90 SpO2: 88%
Physical Exam: normal except for slight dry cough and tubular breath sounds throughout. No rales, wheezes or respiratory distress
Initial Diagnostic Testing:
- CBC: normal except for WBC 12.3
- Chem-7: normal
- Imaging: see plain film below

What is the DDx of tubular breath sounds?
- A) Never heard of this
- B) Pneumonitis
- C) CHF
- D) COPD
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ANSWER: What is the DDx of tubular breath sounds?
- A) Never heard of this – it’s a thing; look it up
- B) Pneumonitis – CORRECT – this is the #1 cause of tubular breath sounds
- C) CHF – ALSO CORRECT. Can cause
- D) COPD – nope
Case conclusion:
- CXR read: In defined bilateral infiltrates can be seen with alveolar edema less likely multifocal infection.
- CT chest read: Extensive nonspecific bilateral airspace disease throughout lungs for which differential diagnosis includes multilobar pneumonia, ARDS & pneumonitis, etc.
- Cardiac labs: Troponin 25 and flat on multiple repeats. BNP normal x2
- Ultimate diagnosis: pneumonitis from MTX
